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Tirzepatide: the week-by-week journey Weeks 1-2 (2.5mg): Most researchers describe this as the "nothing" phase
Therefore, discovering a small molecule GLP-1RA that could be orally administered is a current but extremely challenging research hotspot
Bottom line Wegovy (semaglutide) has special storage requirements that need to be followed to ensure the pens are safe and effective
Clinically meaningful responses in insulin-resistant patients typically include a reduction in fasting insulin of 20-40% and an improvement in HOMA-IR within 8-12 weeks at therapeutic doses, though individual variability is wide [1]
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